Tag Archives: PDE5 inhibitor drugs

How Long Does Tadalafil Take to Work

During the late 90s, people were introduced to a new type of drug called PDE5 inhibitors and this type of drug miraculously treated the male condition called erectile dysfunction (ED).  By using PDE5 inhibitor drugs, a man who is erectile dysfunctioned is now again capable of producing a penile erection, although temporarily, which he can use to have sex.  Since an erection is a necessity when having sex, PDE5 inhibitor drugs are a much welcome discovery by men who have become erection impaired.

Fast forwards to November 2003 when Eli Lilly got their approval from the FDA for Cialis (tadalafil), another competitor in the ED treatment market.  Tadalafil works in the very same way as every PDE5 inhibitor drugs wherein its main mechanism of action is to allow smooth blood flow onto the inside cavities of the penis.  When the penis becomes engorged in blood, it begins to produce an erection despite having erection impairments. This is achieved through selective biochemical processes, which is why when the drug is in effect, a penile erection can only be achieved through sexual stimulation or arousal.

Slowly but surely, tadalafil has gained popularity among those who use ED treatment drugs as tadalafil provides them with the longest potential capacity to produce a penile erection which is in total 36 hours.  This 36 hours of effect time is actually a whopper when compared to the measly 4-10 hours that the competition provides. Continue reading